Dataset of Access to Chiral Rigid Hemicyanine Fluorophores from Tröger Bases and alpha-Imino Carbenes

Chiral hemicyanine fluorophores are afforded in three steps only from Tröger bases via α-imino carbene additions, an original aminal deprotection and Cu(II)-mediated oxidations. The stable benzodiazepinoindolium salts are readily isolated and present (chir)optical properties that can be fine-tuned by late-stage cross-coupling functionalization. The hemicyanine character of dyes was rationalized using first principles.

Publication date

13/08/2020

Retention date11/08/2030

Access levelPublic

SensitivityUndefined

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Laboratory of Professor Jérôme Lacour

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Laboratory of Professor Jérôme Lacour

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