Akt-driven TGF-β and DKK1 Secretion Impairs F508del CF Airway Epithelium Polarity

Set of data on the signaling pathways that shape the airway epithelium, the temporal interplay of which is altered in Cystic Fibrosis, leading to loss of apicobasal polarity. The effect of CFTR modulators was also investigated.

Organizational unit

Cystic Fibrosis & Gap Junctions

Type

Dataset

DOI

10.26037/yareta:tsgknwsj4bd5hah423fxw2ooem

License

Creative Commons Attribution 4.0 International

Keywords

polarity, airway epithelium, cystic fibrosis, bacterial infections, signaling pathways, TGF-β, DKK1, Akt