SNSF_203577_Bactericidal Nanoblades

The main objective of our project is to validate the feasibility of the concept of bactericidal nanoblades that enable the remote elimination of biofilms using a bimodal chemo-mechanical approach. Various protocols will be tested to evaluate the performance of our concept, which combines mechanical destruction and bactericidal action in synergy. Mechanical destruction will be achieved by converting magnetic energy into the rotational movement of remotely controlled anisotropic magnetic particles with different form factors to be evaluated, such as nano-plates, nano-sticks, nano-chains, and micro-magnetic sticks. The bactericidal component will be provided by the release of silver ions by convection, generating a broad-spectrum antimicrobial environment. This strategy will be evaluated on different combinations of bacterial biofilms and surfaces, including bacteria that are very important for the healthcare system and the food industry.

Organizational unit: Materials characterization laboratory_MON_inTECH_HEPIA

Type: Dataset

DOI: 10.26037/yareta:r5shsov6nfelxdt5zzsxx7prei

Embargo access level: Closed

Embargo end date: 16/01/2029

License: Creative Commons Attribution-NonCommercial 4.0 International

Funding agencies: Swiss National Science Foundation

Keywords: Nanotechnology, Nanomaterials, biofilm

Publication date

16/01/2026

Retention date14/01/2036

Access levelClosed

SensitivityUndefined

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Contributors

Milosevic, Irena

Pautu , Vincent

Marger , Laurine

Marger , Fabrice

Mekki, Mustapha

Files

4 Files (14.5 MB)

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            <datacite:creatorName nameType="Personal">Milosevic, Irena</datacite:creatorName>
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            <datacite:creatorName nameType="Personal">Mekki, Mustapha</datacite:creatorName>
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        <datacite:title>SNSF_203577_Bactericidal Nanoblades </datacite:title>
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    <datacite:publisher publisherIdentifier="https://ror.org/01swzsf04" publisherIdentifierScheme="ROR" schemeURI="https://ror.org/">Université de Genève, Yareta</datacite:publisher>
    <datacite:publicationYear>2029</datacite:publicationYear>
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            <datacite:affiliation xsi:type="datacite:affiliation" affiliationIdentifier="https://ror.org/01xkakk17" affiliationIdentifierScheme="ROR" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">[HES-SO] Haute École Spécialisée de Suisse Occidentale</datacite:affiliation>
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            <datacite:contributorName nameType="Personal">Milosevic, Irena</datacite:contributorName>
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        <datacite:date dateType="Issued">2026-01-16T00:00:00Z</datacite:date>
        <datacite:date dateType="Collected">2026-01-16T00:00:00Z/</datacite:date>
        <datacite:date dateType="Created">2026-01-16T13:20:48.198999Z</datacite:date>
        <datacite:date dateType="Updated">2026-03-06T15:36:21.096971Z</datacite:date>
        <datacite:date dateType="Accepted">2026-03-06T15:25:30.048613446Z</datacite:date>
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        <datacite:description descriptionType="Abstract" xml:lang="en">The main objective of our project is to validate the feasibility of the concept of bactericidal nanoblades that enable the remote elimination of biofilms using a bimodal chemo-mechanical approach. Various protocols will be tested to evaluate the performance of our concept, which combines mechanical destruction and bactericidal action in synergy. Mechanical destruction will be achieved by converting magnetic energy into the rotational movement of remotely controlled anisotropic magnetic particles with different form factors to be evaluated, such as nano-plates, nano-sticks, nano-chains, and micro-magnetic sticks. The bactericidal component will be provided by the release of silver ions by convection, generating a broad-spectrum antimicrobial environment. This strategy will be evaluated on different combinations of bacterial biofilms and surfaces, including bacteria that are very important for the healthcare system and the food industry.
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SNSF_203577_Bactericidal Nanoblades

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